Know the Difference: CBD vs. CBG
by Alissa Gardner | 05 October, 2022
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CBD is an incredibly popular cannabinoid at the moment, and for a good reason. It is famous for its relaxing effects, as well as analgesic properties. However, it is worth noting that CBD is not the only cannabinoid that can be found in cannabis plants. In fact, there are quite a few other cannabinoids that are worth checking out. For instance, CBG is currently capturing the interest of researchers and consumers alike.
Researchers came to the conclusion that CBG might be similar to CBD. Both are non-psychoactive, and both have anti-inflammatory, antioxidant, analgesic, and neuroprotective properties. Nevertheless, CBG and CBD are not the same. If you want to learn more, in the article below, you will find a detailed explanation of the differences and similarities between the two, together with answers to frequently asked questions.
What Is CBD?
CBD, which stands for cannabidiol, is a chemical that naturally occurs in cannabis and hemp plants. It was first discovered almost a century ago but did not attract major attention until 1974. That is when scientists discovered that it might have anticonvulsant properties.
Over time, scientists have proved that CBD has a wide range of therapeutic benefits, including anti-nausea and anti-anxiety qualities. Later on, it was found to be an effective treatment for two rare forms of childhood epilepsy. In fact, there’s even a CBD-based drug, Epidiolex, which was approved by the FDA in 2018.
CBD works by interacting with the human endocannabinoid system. Also known as the ECS, it is a network of cannabinoid receptors packed throughout the human body. It has a significant impact on a number of important processes, including memory, learning, and pain control. CBD interacts with the CB1 and CB2 receptors within the ECS. As a result, it can influence some of the processes that the ECS is responsible for.
In recent years, CBD has become incredibly popular, and it should come as no surprise. It has plenty of benefits and, unlike THC, is completely non-intoxicating. In other words, you can use it without having to deal with impaired cognitive function or paranoia. For that reason, CBD products can be found not only in dispensaries but also in a wide range of pharmacies and supermarkets. On top of that, you can buy it in a number of different forms, ranging from full-spectrum CBD oils and topicals to CBD tinctures.
What Is CBG?
CBG, which stands for cannabigerol, is also a cannabinoid that can be found in young hemp and cannabis plants.
The plant naturally produces cannabigerolic acid, and, as it grows, the acid is broken down into cannabidiolic acid and tetrahydrocannabinolic acid. Later on, the two compounds are converted into CBD and THC. Any leftover cannabigerolic acid is converted into CBG.
In spite of the fact that CBG was first discovered in 1964, it did not get much attention, and its properties were the subject of very few studies. Nowadays, research into CBG is in its early stages, but it has already been established that CBG is likely to have a number of therapeutic properties. In addition, it was discovered that just like CBD, CBG might bind to the CB1 and CB2 receptors of the human endocannabinoid system.
Differences Between CBD and CBG
To begin with, these two cannabinoids do not share the same molecular structure – the arrangement of oxygen, carbon, and hydrogen in their molecules varies. Consequently, CBG and CBD interact with the body’s cannabinoid receptors in different ways. It has a significant impact on their bioavailability as well.
CBG and CBD are also different when it comes to how they activate receptors. A study published in 2019 examined how the two compounds bind to the 5-HT1A receptor. It found that CBG acts as an antagonist at that receptor. To put it another way, it binds to it and either blocks or dampens its effects. On the other hand, CBD behaves as an agonist and activates the receptor, which results in a strong anti-nausea effect. So, in spite of the fact that the two compounds are similar, they have opposing effects when they bind to the same receptor.
CBD and CBG also seem to differ when it comes to appetite stimulation. In 2016, researchers observed that CBG encouraged rats to eat twice as much food as they normally would. Conversely, CBD was found to reduce total food intake.
Health Benefits of CBD and CBG
There is not that much research on the topic of CBG and its therapeutic effects. However, some clinical trials offer a bit of insight into how it might interact with cannabinoid receptors in the body.
Like CBD, CBG is non-intoxicating. What is more, it appears to have a number of interesting benefits, such as antibiotic properties and appetite stimulation. In one study, it was discovered to be a potential treatment for experimental inflammatory bowel disease. In another one, it turned out to be effective for treating MRSA bacterial infections.
Due to the fact that interest in CBG is steadily growing, it is likely that we will hear more about it in the near future. Soon enough, we might get a much better understanding of how CBG works and the potential health benefits it offers.
But just like with CBG, there is more to learn. The majority of studies on the topic were conducted on animals. On that account, more human trials are needed to help us understand what effects both CBD and CBG have on the human body.
What Are the Best Ways to Take CBG?
You can take CBG in a number of different ways. For example, you could buy a bottle of CBG oil or opt for some CBG topicals.
In case you do not know where to start, here is a short list of the most popular CBG products on the market. Once you are done reading, finding a CBG product that you are going to enjoy using should become much easier!
CBG oil is a mixture of CBG extract and carrier oil, such as olive oil or avocado oil. It is best taken sublingually. In other words, you put it under the tongue for thirty to sixty seconds. During that time, the CBG is going to be absorbed into your bloodstream. Next, you just swallow the oil down, and that is it. If this is not something to your liking, you could always add a few drops of CBG oil to your favorite beverage or use it as a salad dressing. It is up to you!
CBG gummies are sweets with added CBG extract. There are perfect for people with a sweet tooth. They might also be worth considering if you are not a fan of the earthy aftertaste of CBG oils; CBG gummies come in a wide range of flavors, such as tropical fruit or berries. Unfortunately, they might not be the best choice if you have to watch your sugar intake or if you suspect that you might end up eating an entire bag in one sitting. While CBG gummies are delicious, they are not meant to be eaten in large quantities.
CBG tinctures are concentrated CBG extracts. The most potent tinctures contain alcohol, but there are some with oils instead. While oil-based tinctures are not as strong as those with alcohol, they are an excellent choice for people who do not want or cannot drink alcohol.
CBG capsules are the most discreet way of taking your daily dose of CBG. They consist of an outer shell and a filling that contains cannabigerol extract. Using such capsules is incredibly easy – you just need to pop one capsule into your mouth and swallow it down with water.
CBG topicals are creams and salves that are meant to be applied topically. They usually contain CBG extract and various nourishing ingredients, such as jojoba oil and argan oil. They work best for people who are either looking for quick topical pain relief or want their skin to look healthy and radiant.
Are There Different Types of CBG Products?
CBG products can be divided into three types, namely full-spectrum CBG, broad-spectrum CBG, and CBG isolate. It is important that you familiarize yourself with what these product types have to offer and choose the one that suits your needs and preferences best.
Full-spectrum CBG products, such as full-spectrum CBG oil, contain not only CBG but also trace amounts of THC, CBD, and other cannabinoids, as well as terpenes and flavonoids. According to scientists, these different compounds work together creating the entourage effect. As a result, they end up being much stronger than broad-spectrum and isolate products.
This type of CBG product contains a wide range of cannabinoids, with the exception of THC. While it appears to be a bit weaker in comparison to full-spectrum CBG, it is definitely worth looking into. In fact, it might be just what you are looking for if you are not a fan of THC and still want to benefit from the aforementioned entourage effect.
CBG isolate is an extract that contains purified CBG and almost nothing else. Other hemp compounds that are naturally present in the Cannabis sativa plant are eliminated during the manufacturing process. CBG isolate is then sold in the form of a powder, which can be added to almost any product type. It is a great option if you are looking for the purest form of CBG, without any other cannabinoids.
How Long Does It Take for CBG to Take Effect?
It depends on the CBG product that you are using and the way you are using it. For instance, if you are using CBG oil sublingually, it should take effect in fifteen to thirty minutes. The same goes for CBG topicals. Meanwhile, CBG edibles, such as CBG gummies, might take up to two hours to kick in, as they have to be digested first.
What Is Better for Anxiety? – CBD vs. CBG
While research on the topic is still at a preclinical stage, early studies and anecdotal evidence seem to suggest that both CBD and CBG can be used to treat anxiety. As mentioned above, CBD is thought to be able to bind to the cannabinoid receptors in the brain. As a result, it is capable of regulating mood. CBG might work in a similar way.
While both CBG and CBD are considered to be well-tolerated and have few side effects, consider talking to a qualified medical professional before using them for anxiety. For best results, it should be an additional to your treatment program for anxiety. For instance, instead of relying on CBG alone, you could also go to a psychiatrist and start attending therapy sessions with a licensed psychotherapist.
What Are the Negative Effects of CBG?
If you are following relevant directions on product labels, the possibility that you will experience any negative effects is really low. CBG has been proven to be a well-tolerated compound. Just like with CBD products like CBD oil, if you end up taking too much CBG, you may experience anxiety, dry mouth, dizziness, and nausea. These negative effects should subside in three to five hours. If they do not subside, you might want to stop taking your CBG product of choice and talk to a doctor.
With that in mind, you should start with a lower dosage and gradually increase it over the course of a few days or weeks. By doing so, you will give your body the time it needs to get used to CBG and lower your likelihood of experiencing any adverse effects.
Does CBG Interact With Any Medications?
There is little to no information available when it comes to how CBG interacts with medications. Nevertheless, you might want to avoid taking it with prescription medications, such as cholesterol medications, corticosteroids, and immunosuppressants. If you want to go through with it, consult a qualified healthcare professional beforehand.
How Much CBG Should I Take Daily?
There is not enough information regarding what an appropriate dosage of CBG is. It depends on a number of different factors, such as age, underlying conditions, liver metabolism, weight, and the type of product that you are using.
If you want to figure out what dosage suits you best, start slow and gradually increase the dosage until you are satisfied. For instance, if the recommended dose listed on the packaging ranges from 10 milligrams to 50 milligrams per day, start with 10 milligrams. After a few days, bump your dosage up to 15 milligrams. Repeat the process until you get the desired effects.
For best results, you should start journaling your CBG usage. You can either use your phone or a pen and paper. Every entry should include the date and your dosage. In addition, write down how you are feeling thirty to forty-five minutes after taking CBG. It will make figuring out what dosage makes you feel your best a bit easier.
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